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rRNA transcription is integral to liquid-liquid phase separation and maintenance of nucleolar structure

‍Dash S, Lamb MC, Lange JJ, McKinney MC, Tsuchiya D, Guo F, Zhao X, Corbin TJ, Kirkman ME, Delventhal K, Moore EL, McKinney SA, Shiang R, Trainor PA.

PLOS Genetics

Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development

Falcon KT, Watt KEN, Dash S, Zhao R, Sakai D, Moore EL, Fitriasari S, Childers M, Sardiu ME, Swanson S, Tsuchiya D, Unruh J, Bugarinovic G, Li L, Shiang R, Achilleos A, Dixon J, Dixon MJ, Trainor PA.

Proc Natl Acad Sci

Nucleolin loss-of-function leads to aberrant FGF signaling
and craniofacial anomalies

Dash S, Trainor PA.

Med23 Regulates Sox9 Expression during Craniofacial Development

‍Dash S, Bhatt S, Falcon KT, Sandell LL, Trainor PA

J Dent Res

The Mediator subunit, Med23 is required for embryonic survival and regulation of canonical WNT signaling during cranial ganglia development

Dash S, Bhatt S, Sandell L, Seidel C, Ahn Y, Krumlauf R, Trainor PA

The development, patterning and evolution of neural crest cell differentiation into cartilage and bone

Dash S, Trainor PA

The master transcription factor SOX2, mutated in anophthalmia/microphthalmia, is post-transcriptionally regulated by the conserved RNA-binding protein RBM24 in vertebrate eye development.

Dash S, Brastorm LK, Patel SD, Scott CA, Slusarksi D C, Lachke SA

Human Molecular Genetics

The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology

Barnum C.E., Saai S.A., Patel S.D., Cheng C., Anand D., Xu X., Dash S., Siddam A.D., Glazewski L., Paglione E., Polson S., Chuma S., Mason R.W., Wei, S., Batish M., Fowler V.M., Lachke S.A.

Human Molecular Genetics

Express: A database of transcriptome profiles encompassing known and novel transcripts across multiple development stages in eye tissues

Budak G., Dash S., Srivastava R., Lachke S.A., Janga S.C.

Experimental Eye Research

Transcriptome analysis of developing lens reveals abundance of novel transcripts and extensive splicing alterations

Srivastava R., Budak G., Dash S., Lachke S.A., Janga S.C.

Scientific Reports

RNA Binding Proteins in Eye Development and Disease: Implication of Conserved RNA Granule Components

Dash S., Siddam A.D., Barnum C.E., Janga S.C., Lachke S.A.

Deficiency of the RNA binding protein caprin2 causes lens defects and features of peters anomaly

Dash S., Dang C.A., Beebe D.C., Lachke S.A.

Development Dynamics

Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract

Agrawal S.A., Anand D., Siddam A.D., Kakrana A., Dash S., Scheiblin D.A., Dang C.A., Terrell A.M., Waters S.M., Singh A., Motohashi H., Yamamoto M., Lachke S.A.

Anatase Titanium Dioxide Nanoparticles in Mice: Evidence for Induced Structural and Functional Sperm Defects after Short-, but not Long-, term Exposure

Smith M.A., Michael S.R., Aravindan G. R., Dash S., Shah I., Galileo D.S., Martin-DeLeon P.A.

Asian Journal of Andrology

Hyaluronidase 2: A Novel Germ Cell Hyaluronidase with Epididymal Expression and Functional Roles in Mammalian Sperm

Modelski M., Menlah G., Wang Y., Dash S., Wu K., Galileo D.S., and Martin-DeLeon P.A.

Biology of Reproduction

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